The short answer is No. For one thing, it's just easier, cheaper and quicker for some applicants to e-mail a resume, as opposed to faxing or mailing it. You don't want to discourage job applicants.
You may want to purchase a virus protection software program, which are relatively inexpensive and usually pretty good at spotting viruses. Be sure you purchase an updated version of the software.
Another trick: Ask applicants to cut and paste their resumes into your e-mail messages. The resume may not look as good, but the information is there and the virus usually isn't.
SOURCE: Human Resources Net, January 1999.